How is the SAECG used clinically?

How is the SAECG used clinically?_17.jpg

Late potentials have been detected in 73-92% of patients with sustained and inducible ventricular tachycardia after MI. Late potentials also have been identified in patients with nonischemic heart disease and ventricular tachycardia, such as those with dilated cardiomyopathy. Early use of thrombolytic agents reduces the prevalence of late potentials after coronary occlusion and therefore the risk of sudden death, ventricular fibrillation, and tachycardia.

Late potentials after MI are an independent marker of patients at high risk for ventricular tachycardia. SAECG results combined with other noninvasive data (e.g., Holter, ETT, ejection fraction) provide a highly sensitive and highly specific method of identifying patients at risk for ventricular tachycardia or sudden death.


DiMarco JP, Philbrick JT: Use of ambulatory electrocardiographic (Holter) monitoring. Ann Intern Med 113:53-68, 1990.

El-Sherrif N, Ursell SN, Bekheit S, et al: Prognostic significance of the signal-average ECG depends on the time of recording in the post-infarction period. Am Heart J 118:256, 1989.

Gomes JA, Winters SL, Martinson M, et al: The prognostic significance of quantitative signal-averaged variables relative to clinical variables, site of myocardial infarction, ejection fraction and ventricular premature beats: A prospective study. J Am Coll Cardiol 13:377, 1989.

Hauer RN, Lie KI, Liem KL, Dureer D: Long-term prognosis in patients with bundle branch block complicating acute anteroseptal infarction. Am J Cardiol 49:1581, 1982.

Kennedy HL: Long-term (Holter) electrocardiogram recordings. In Zipes DP. Jalife J (eds): Cardiac

Electrophysiology: From Cell to Bedside. Philadelphia, W.B. Saunders, 1990, p 791.

Kuchar DL, Thorbum CW, Sammel NL: Prediction of serious arrhythmic events after myocardial infraction: Signal-averaged electrocardiogram, Holter monitoring and radionuclide ventriculography. J Am Coll Cardiol 9:531, 1987.

Langer A, Freeman MR, Josse RG, et al: Detection of silent myocardial ischemia in diabetes mellitus. Am J Cardiol 67:1073, 1991.

Turitto G, Fontaine JM, Ursell SN, et al: Value of the signal-averaged electrocardiogram as a predictor of the results of programmed stimulation in nonsustained ventricular tachycardia. Am J Cardiol 61:1272, 1988.

Van Ravenswaaij-Arts MA, Kollee AA, Hopman JC, et al: Heart rate variability. Ann Intern Med 118:436-47, 1993.

Yeung AC, Barry J, Orav J, et al: Effects of asymptomatic ischemia on long-term prognosis in chronic stable coronary disease. Circulation 83:1598, 1991.

How is the SAECG used clinically?_17.jpg

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